Career opportunities | Directory | Events | Campus News | Journal Club
NATIONAL BRAIN RESEARCH CENTRE
Home E-mail Home Home Guest Book Guest Book
Prof. Subrata Sinha
Director
  Email : subrata.sinha[AT]nbrc[dot]ac[dot]in, director[AT]nbrc[dot]ac[dot]in
 
Home

Glial tumors are common primary brain tumors that are malignant in nature and have been shown to originate in astrocytes, oligodendroglial cells and the ependyma. At the genetic and molecular levels gliomas show several alterations which seem to accelerate growth-factor mediated cell proliferation and render malignancy. Such multifactorial processes underlie the heterogeneity of these tumors which leave several open ends that demand extensive research. Thus, advances in the understanding that may be achieved through molecular and translational glioma research can aid in the identification of diagnostic, prognostic and/or predictive markers as well as potential drug targets. To this end, Prof Sinha’s primary research interests aim at understanding the molecular biology of glial tumor progression; studying genomic instabilities that may contribute to alterations in tumor phenotype which in turn may confer drug resistance; study of cellular responses to stress including hypoxia; transcriptional gene silencing and its implications in tumor biology and therapeutics; and, development of recombinant antibody methods for testing potential use in oncotherapeutics.

 
 
 
ipv6 ready
Admission 2017 Result | Admission 2017 | IAN 2016 | Internal Resources
Tenders | Right to Information | Governance | Contact Us
© Copyrights 2017 All Rights Reserved, National Brain Research Centre
Manesar, Gurgaon Dist. Haryana-122 051, India