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Prof. Pravat K. Mandal
Scientist-VI / Professor
  Email : pravat[AT]nbrc[dot]ac[dot]in, pravat[dot]nbrc[AT]gov[dot]in
  Lab Website
1. Pravat K Mandal*, Krity Kansara and Aroma Dabas "The GABA–Working Memory Relationship in Alzheimer's Disease" Journal of Alzheimer's Disease Report 1 43-45 (2017)
2. Pravat K Mandal*, Deepika Shukla, Varan Govind, Yves Boulard and Lars Ersland "Glutathione Conformations and Its Implications for in vivo Magnetic Resonance Spectroscopy" Journal of Alzheimer's Disease, Volume 59 (2) 537-541 (2017)
3. Xanthate D. Suvarnalata, Sumiti Saharan, Patha Raghunathan, Pravat K Mandal* Stimulus-dependent Modulation of Working Memory for Visual Identity Monitoring: An functional MRI study" Brain and Cognition, Vol 102:55-64 (2016)
4. Pravat K Mandal, S Saharan, O Penn, V Fodale Anesthesia Issues in Central Nervous System Disorders Current Aging Science, 9(2):116-43 (2016)
5. Monika Grewal; Aroma Dabas; Sumiti Saharan1; Peter B. Barker; Richard A.E. Edden; and Pravat K. Mandal*, "GABA Quantitation using MEGA-PRESS: Regional and Hemispheric Differences" Journal of Magnetic Resonance Imaging 44(6):1619-1623(2016)
6. Pravat K Mandal, Sumiti Saharan, Manjari Tripathi and Geetanjali Murari "Brain Glutathione Levels – A Novel Biomarker for Mild Cognitive Impairment and Alzheimer’s Disease" Biological Psychiatry Vol 78(10):702-10 (2015)
7. Pravat K. Mandal, Sumiti Saharan, Sara Khan, Mithun James "Apps for Dementia Screening: A Cost-effective and Portable Solution", Journal of Alzheimer's Disease, Vol 47, Number 4 (2015)
8. Pravat K Mandal*, Karen Ritchie,and Vincenzo Fodale* Anesthetics and its Impact on the Brain and Alzheimer’s Disease, Journal of Alzheimer's disease (2014) Editorial Vol 39 No 2 223-225.
9. Jitesh Joshi, Sumiti Saharan and Pravat Mandal* " BOLDSync: A MATLAB-based Toolbox for Synchronized Stimulus Presentation in Functional MRI study" Journal of Neuroscience Methods (2014 ) 223 pages 123– 132
10. Sumiti Saharan and Pravat K Mandal * "Emerging Role of Glutathione in Alzheimer's Disease. Journal of Alzheimer's disease. Vol 40 2014 (519-529)
11. Pravat K Mandal "Brain Metabolic Mapping with MRS – A Potent Non-invasive Tool for Clinical Diagnosis of Brain Disorders". American Journal of Neuroradiology ,(Editorial in PRESS) Special Issue Metabolic Brain Mapping.
12. R Prashanth, SD Roy, PK Mandal, S Ghosh "Automatic Classification and Prediction Models for Early Parkinson’s Disease Diagnosis from SPECT Imaging" Expert Systems with Applications; (2014) Vol 41; Pages 3333–3342
13. Pravat K. mandal*, H. Akolkar, and Manjari Tripathi "Mapping of Hippocampal pH and Neurochemicals from in vivo Multi-Voxel 31P Experiments in Healthy Normal Young Male/Female, Mild Cognitive Impairment, and Alzheimer’s Disease" Journal of Alzheimer Disease Vol 31 75-86(2012)
14. Pravat K. Mandal*, Rashima Mahajan, Ivo D. Dinov "Structural Brain Atlases: Design, Rationale and Applications in Normal and Pathological Cohorts" Journal of Alzheimer’s Disease vol 31 169-188 (2012)
15. Pravat K mandal, Jitesh Joshi, Sumiti Saharan "Visuospatial Perception: An Emerging Biomarker for Alzheimer's Disease. Journal of Alzheimer's Disease. vol 31 117-136(2012).
16. Pravat K Mandal* "Proton Magnetic Resonance Spectroscopic Signal Processing for the Quantitation of Neurometabolites" European Journal of Radiology 653– 664, 81(2012).
17. Pravat K. mandal*, Manjari Tripathi and Sreedevi Sugunan "Brain oxidative stress: Detection and mapping of anti-oxidant marker ‘Glutathione’ in different brain regions of healthy male/female, MCI and Alzheimer patients using non-invasive magnetic resonance spectroscopy" Biochemical Biophysical Research Communications 43-47, 417(2012)
18. Pravat K. Mandal* "Predictive Biomarkers for Alzheimer’s Disease using State-of-the-Art Brain Imaging Techniques " Journal of Alzheimer's Disease vol 31 s1-s3 ( 2012)
19. Pravat K Mandal* and H. Akolkar " A new experimental approach and signal processing scheme for the detection and quantitation of 31P brain neurochemicals from in vivo MRS studies" Biochemical and Biophysical Research communications, Vol 412, Pages 302-306 (2011)
20. Pravat K Mandal* and Vinenzo Fodale " Anesthetics and Alzheimer Disease " Editorial, Journal of Alzheimer Disease, 22, 135-137 (2010)
21. Pravat K Mandal* and Manisha Ahuja "Comprehensive Magnetic Resonance Spectroscopic Studies on Interactions of Abeta with Different Molecular Sized Anesthetics" Journal of Alzheimer Disease, 22, 27-34 (2010)
22. Fodale, Vinenzo; Ritchie, Karen; Rasmussen, Lars ; and Pravat K Mandal* (2010). "Anesthetics and Alzheimer's Disease: Background and Research" J Alzheimer Disease, 22, 1-3 (2010)
23. Daniela Schifilliti, Letterio B. Santamaria, Giovanni Rosa, Gianfranco Di Nino, Pravat K. Mandal, and Vincenzo Fodale "Cholinergic Central System, Alzheimer’s Disease and Anesthetics Liaisons: a vicious circle?" Journal of Alzheimer Disease, 22, 35-41 (2010).
24. Pravat K Mandal*, Neel S Bhavesh, Virender S. Chauhan and Vincenzo Fodale  "NMR investigations of Aβ peptide interactions with propofol at clinically relevant concentrations with and without aqueous halothane solution" Journal of Alzheimer Disease, (21:1303-1309, 2010)
25. Pravat K Mandal*, Virgil Simplaceanu  and Vincenzo Fodale : "Intravenous Anesthetic Diazepam does not induce Amyloid beta-peptide Oligomerization but Diazepam Co-administered with Halothane Oligomerizes Amyloid Beta-peptide: An NMR study"  Journal of Alzheimer Disease (Vol 20(1) pages 127-134, 2010)
26. V. Fodale, L.B. Santamaria, D. Schifilliti and P. K. Mandal : "Anaesthetics and post-operative cognitive dysfunction: a pathological mechanism mimicking Alzheimer’s Disease" Anesthesia Journal (Vol 65(4) page 388-395, April 2010).
27. Pravat K. Mandal* and Vincenzo Fodale :" Smaller molecular-sized anaesthetics oligomerize Abeta peptide simulating Alzheimer’s disease: a relevant issue" European Journal of Anesthesiology, Vol 26(10) Page 805-806 , 2009 - Editorial
28. Pravat K. Mandal*, Daniela Schifilliti, Federica Mafrica, and Vincenzo Fodale "Inhaled Anesthetics and Cognitive Performance" Drugs of Today, (45: 47-54, 2009).
29. Pravat K Mandal*, Vincenzo Fodale "Isoflurane and desflurane at clinically relevant concentrations induce amyloid beta-peptide oligomerization: An NMR study" Biochemical and Biophysical Research Communications. (379: 716-720, 2009)
30. Pravat K. Mandal*, J. W. Pettegrew,” Abeta Peptide interactions with Isoflurane, Propofol, Thiopental and combined Thiopental with Halothane: A NMR  Study” Biochemica Biophysica Acta, Biomembrane, (1778: 2633-2639 , 2008).
31. Pravat K. Mandal*, J. W. Pettegrew,” Clinically relevant concentration determination of inhaled anesthetics (halothane, soflurane, sevoflurane and desflurane) by 19F NMR” Cell Biochemistry and Biophysics, (52:31-35, 2008)
32. Pravat K Mandal*, “Magnetic Resonance Spectroscopy (MRS) and its application in Alzheimer’s Disease”  Concepts in Magnetic Resonance Part A (30, 40-65, 2007).
33. Pravat K. Mandal*, J. W. Pettegrew, E. Masliah,., R. L. Hamilton, and R. Mandal “Interaction between Aβ Peptide and α Synuclein: Molecular Mechanisms in Overlapping Pathology of Alzheimer’s and Parkinson’s in Dementia with Lewy Body disease” Neurochemical Research, 31,1153-1162, (2006)
34. Pravat K. Mandal* and A. Majumdar, “A Comprehensive Discussion of HMQC and HSQC Pulse Sequences ” Concepts In Magnetic Resonance, 20A, 1-23 (2004)
35. Pravat K. Mandal and Jay W. Pettegrew, “Alzheimer Disease: NMR studies of AsialoGM1 and trisialo (GT1b) ganglioside interactions with Ab(1-40) peptide in Membrane mimic environment” Neurochemical. Research, 29, 447-453 (2004)
36. Pravat K. Mandal, R. McClure, J. W. Pettegrew “Interactions of Ab;(1-40)  with Glycerophosphocholine and Intact Erythrocyte Membranes: Fluorescence and Circular Dichroism Studies” (Neurochemical Research, 29, 2273-2279, 2004)
37. Pravat K. Mandal,  Pettegrew JW  “Alzheimer’s disease: soluble oligomeric Aβ(1.40) peptide in membrane mimic  environment from solution NMR and circular dichroism studies” (Neurochemical Research, 29, 2267-2272, 2004)
38. Yushmanov, V. E.; Pravat K Mandal; Liu, Z. W NMR structure and backbone dynamics of the extended second transmembrane domain of the human neuronal glycine receptor alpha(1) subunit Biochemistry Volume: 42 Pages: 3989-3995(2003)
39. MADHU, PK; MANDAL, Pravat K; MULLER, N Cross-correlation effects involving Curie spin relaxation in methyl groups. JOURNAL OF MAGNETIC RESONANCE Volume: 155 Issue: 1 Pages: 29-38 ( 2002 )
40. Tang, P.; Mandal, P. K.; Zegarra, M Effects of volatile anesthetic on channel structure of gramicidin A Biophysical Journal Volume: 83 Issue: 3 Pages: 1413-1420 (2002)
41. Tang, P.; Mandal, Pravat K.; Xu, Y NMR structures of the second transmembrane domain of the human glycine receptor alpha(1) subunit: Model of pore architecture and channel gating. Biophysical Journal Volume: 83 Pages: 252-262 (2002)
42. Pravat K. Mandal*, “Complete NMR Spectroscopic Assignment of a Neuronal Transduction Protein” Monatshefte  fur Chemie, 133,205-217 (2002)
43. MADHU, PK; GRANDORI, R; HOHENTHANNER, K; Pravat K Mandal, N. Muller Geometry dependent two-dimensional heteronuclear multiplet effects in paramagnetic proteins JOURNAL OF BIOMOLECULAR NMR Volume: 20 Pages: 31-37 ( 2001)
44. SCHAFFER, C; MULLER, N; MANDAL, PK A pyrophosphate bridge links the pyruvate-containing secondary cell wall polymer of Paenibacillus alvei CCM 2051 to muramic acid; GLYCOCONJUGATE JOURNAL Volume: 17 Pages: 681-690 ( 2000)
45. Pravat K. Mandal, P. K. Madhu and N. Muller, “Nuclear Magnetic Relaxation of Methyl Protons in a Paramagnetic Protein: Cross-correlation Effects” Chemical Physics Letters, 320, 269-276 (2000)
46. H. Tochio, Q. Zhang, Pravat K. Mandal, M. Li and M. Zhang, “Solution Structure of the Extended Neuronal Nitric Oxide Synthase PDZ Domain Complexed with an Associated Peptide” Nature Structural Biology, 6, 417-421 (1999)
47. de Ropp, Pravat K. Mandal, GN Lamar, “Solution 1H NMR Investigation of the Heme Cavity and Substrate Binding site of Cyanine-Inhibited Horseradish peroxidase” Biochemistry, 38, 1077-1086 (1999)
48. de Ropp, Pravat K. Mandal, S. Braur and GN Lamar, “Solution NMR Study of the Electronic and Molecular Structure of Heme Cavity in High Spin Resting State Horseradish Peroxidase” Journal of American Chemical Society, 119, 4732-4739 (1997)
49. Pravat K. Mandal, B. Sinha, P. T. Manoharan and R. Ramasesha, “Diagrammetic Valence Bond Studies on Hemocyanin” Theoretica Chemica Acta, 93, 1-16 (1996)
50. Asokan, A.; Mandal, Pravat K.; Varghese, B, Manoharan, P. T. Structure and magnetism of an exchange coupled system: An NMR approach Proceedings of the Indian Academy of Sciences-Chemical Sciences Volume: 107 Issue: 4 Pages: 281-295 ( 1995)
51. Pravat K. Mandal and P. T. Manoharan, “A Comprehensive Study of Exchange Coupling in a Macrocyclic Binuclear Copper (II) Complex in a Solid and Solution States” Inorganic Chemistry, 34, 270-277 (1995)
52. Pravat K. Mandal and P. T. Manoharan, “Effect of Fifth Coordination Site on the Spin States of Bis (Benzoylacetylacetanato) Bis pyridine dicopper (II) Complex” Chemical Physics Letters, 210, 463-470 (1993)
53. Pravat K. Mandal, B. Sinha, P. T. Manoharan and S. Ramasesha, “Theoretical Studies of Spin States of Macrocyclic Aza-amido Binuclear Copper (II) Complexes ” Chemical Physics Letters, 191, 448-454 (1992)
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